Fully Funded Postdoctoral Opportunity in Neuroscience, Neuroinflammation, and Alzheimer's DiseaseResearchers interested in neuroscience, neuroimmunology, and neurodegenerative diseases have an exciting opportunity to join the Department of Medical and Molecular Genetics at Indiana University School of Medicine as a Postdoctoral Fellow. This position offers the opportunity to conduct cutting-edge research focused on understanding the role of microglia in Alzheimer's disease and developing novel therapeutic strategies to combat neurodegeneration.Position OverviewThe Department of Medical and Molecular Genetics at Indiana University School of Medicine is recruiting a highly motivated Postdoctoral Fellow to join the research laboratory of Dr. Miguel Moutinho at the Stark Neurosciences Research Institute. The research team investigates how microglial cells contribute to Alzheimer's disease pathogenesis and neurodegeneration. Using advanced genomic, transcriptomic, imaging, and functional approaches, the laboratory aims to identify therapeutic targets and biomarkers that may improve the diagnosis and treatment of Alzheimer's disease. This is an excellent opportunity for early-career researchers seeking advanced training in neuroscience and neuroimmunology within a collaborative and multidisciplinary environment. Research AreasThe successful candidate will contribute to projects involving:Alzheimer's Disease ResearchInvestigating the biological mechanisms that drive Alzheimer's disease progression and neurodegeneration.Microglial BiologyUnderstanding how microglia influence brain health and disease through immune and inflammatory pathways.NeuroinflammationExploring neuroimmune interactions and inflammatory signaling pathways associated with neurodegenerative disorders.NeurogeneticsStudying genetic risk factors that contribute to Alzheimer's disease susceptibility and progression.Biomarker DiscoveryIdentifying novel biomarkers that can improve disease diagnosis, prognosis, and treatment monitoring.Key Research TechniquesResearchers in the laboratory utilize state-of-the-art methodologies including:• Genomics • Transcriptomics• Advanced microscopy• Functional assays• Flow cytometry• Cell culture systems• Mouse models• Molecular biology techniques• Neurodegeneration models• Imaging technologiesEligibility CriteriaRequired QualificationsPhD in:• Neuroscience• Molecular Biology• Immunology• Genetics• Biomedical Sciences• Related scientific disciplines• Strong research background in neuroscience or neurobiology• Highly Desirable ExperienceCandidates with experience in the following areas are strongly encouraged to apply:• Microglial biology• Neuroinflammation• Alzheimer's disease research• Mouse models• Cell culture• Biological imaging• Preferred SkillsExperience with one or more of the following techniques is advantageous:• Neurodegeneration models• Microglial functional assays• Biochemical assays• Flow cytometry• Transcriptomic analysis• Advanced microscopyCandidate ProfileThe ideal applicant should demonstrate:• Strong analytical and problem-solving abilities• Excellent written and verbal communication skills • Ability to work independently and collaboratively • Experience in data collection, analysis, and interpretation • Interest in manuscript writing and grant development • Commitment to scientific excellence • Ability to mentor graduate students and junior researchersBenefits of Joining Indiana University School of Medicine• Successful candidates will benefit from:• Access to world-class neuroscience research facilities• Collaboration with multidisciplinary research teams• Professional development opportunities• Scientific mentoring and career guidance• Opportunities to publish in leading journals• Experience in grant writing and research leadership• Exposure to cutting-edge Alzheimer's disease researchAbout the Research ProgramThe laboratory's overarching goal is to understand how microglial functions influence Alzheimer's disease progression and how these pathways can be targeted therapeutically. Researchers are particularly interested in leveraging the phenotypic plasticity of microglia to identify interventions that produce beneficial outcomes in neurodegenerative disease. The work has the potential to contribute to the development of new therapies and biomarkers for Alzheimer's disease, one of the most significant healthcare challenges worldwide. Application InformationApplications will be reviewed on a rolling basis until the position is filled.Principal InvestigatorDr. Miguel Moutinho, PharmD, PhDAssistant ProfessorDepartment of Medical and Molecular GeneticsStark Neurosciences Research InstituteIndiana University School of MedicineEmail: [email protected]Position DetailsInstitution: Indiana University School of MedicineDepartment: Medical and Molecular GeneticsLocation: Indianapolis, Indiana, USAPosition Type: Postdoctoral FellowPosting Number: IUSM-02444-2026Why This Opportunity Stands OutThis position provides an outstanding opportunity for researchers interested in Alzheimer's disease, neuroimmunology, and neurodegeneration to develop expertise in one of the fastest-growing areas of biomedical research. The combination of advanced technologies, interdisciplinary collaboration, and strong mentorship makes this fellowship particularly attractive for scientists seeking an academic or industry research career. 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